Which of the following statements correctly describe co-factors?
a. Co-factors are non-protein constituents bound to an enzyme to make it catalytically active.
b. The protein portion of such an enzyme is called the apoenzyme.
c. The holoenzyme is the apoenzyme plus the co-factor. (Inferred knowledge)
d. There are three kinds of cofactors: prosthetic groups, co-enzymes, and metal ions.
e. Prosthetic groups are organic compounds that are loosely bound to the apoenzyme.
f. Co-enzymes are also organic compounds, but their association with the apoenzyme is transient.
g. Metal ions are not considered co-factors.